Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients

Background: Decreased skeletal muscle mass index (SMI) is a major complication of severe chronic heart failure (HF), but no appropriate indices have been developed to predict decreased SMI. Methods and Results: We enrolled patients with a structural heart disease or history of HF and collected body...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuji, Shuhei, Koyama, Satoshi, Taniguchi, Ryoji, Fujiwara, Takako, Fujiwara, Hisayoshi, Sato, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Circulation Society 2019
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897544/
https://www.ncbi.nlm.nih.gov/pubmed/33693083
http://dx.doi.org/10.1253/circrep.CR-19-0053
_version_ 1783653691191984128
author Tsuji, Shuhei
Koyama, Satoshi
Taniguchi, Ryoji
Fujiwara, Takako
Fujiwara, Hisayoshi
Sato, Yukihito
author_facet Tsuji, Shuhei
Koyama, Satoshi
Taniguchi, Ryoji
Fujiwara, Takako
Fujiwara, Hisayoshi
Sato, Yukihito
author_sort Tsuji, Shuhei
collection PubMed
description Background: Decreased skeletal muscle mass index (SMI) is a major complication of severe chronic heart failure (HF), but no appropriate indices have been developed to predict decreased SMI. Methods and Results: We enrolled patients with a structural heart disease or history of HF and collected body composition and blood sample data, including serum amino acid concentration. On multivariate logistic regression analysis and receiver operating characteristic curve analysis, serum branched-chain amino acid (BCAA) concentration was a significant predictor of decreased SMI at 1-year follow-up. Conclusions: Serum BCAA concentration at baseline was significantly associated with decreased SMI at 1-year follow-up.
format Online
Article
Text
id pubmed-7897544
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Japanese Circulation Society
record_format MEDLINE/PubMed
spelling pubmed-78975442021-03-09 Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients Tsuji, Shuhei Koyama, Satoshi Taniguchi, Ryoji Fujiwara, Takako Fujiwara, Hisayoshi Sato, Yukihito Circ Rep Rapid Communication Background: Decreased skeletal muscle mass index (SMI) is a major complication of severe chronic heart failure (HF), but no appropriate indices have been developed to predict decreased SMI. Methods and Results: We enrolled patients with a structural heart disease or history of HF and collected body composition and blood sample data, including serum amino acid concentration. On multivariate logistic regression analysis and receiver operating characteristic curve analysis, serum branched-chain amino acid (BCAA) concentration was a significant predictor of decreased SMI at 1-year follow-up. Conclusions: Serum BCAA concentration at baseline was significantly associated with decreased SMI at 1-year follow-up. The Japanese Circulation Society 2019-09-27 /pmc/articles/PMC7897544/ /pubmed/33693083 http://dx.doi.org/10.1253/circrep.CR-19-0053 Text en Copyright © 2019, THE JAPANESE CIRCULATION SOCIETY This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Rapid Communication
Tsuji, Shuhei
Koyama, Satoshi
Taniguchi, Ryoji
Fujiwara, Takako
Fujiwara, Hisayoshi
Sato, Yukihito
Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients
title Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients
title_full Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients
title_fullStr Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients
title_full_unstemmed Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients
title_short Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients
title_sort association of serum amino acid concentration with loss of skeletal muscle mass after 1 year in cardiac rehabilitation center patients
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897544/
https://www.ncbi.nlm.nih.gov/pubmed/33693083
http://dx.doi.org/10.1253/circrep.CR-19-0053
work_keys_str_mv AT tsujishuhei associationofserumaminoacidconcentrationwithlossofskeletalmusclemassafter1yearincardiacrehabilitationcenterpatients
AT koyamasatoshi associationofserumaminoacidconcentrationwithlossofskeletalmusclemassafter1yearincardiacrehabilitationcenterpatients
AT taniguchiryoji associationofserumaminoacidconcentrationwithlossofskeletalmusclemassafter1yearincardiacrehabilitationcenterpatients
AT fujiwaratakako associationofserumaminoacidconcentrationwithlossofskeletalmusclemassafter1yearincardiacrehabilitationcenterpatients
AT fujiwarahisayoshi associationofserumaminoacidconcentrationwithlossofskeletalmusclemassafter1yearincardiacrehabilitationcenterpatients
AT satoyukihito associationofserumaminoacidconcentrationwithlossofskeletalmusclemassafter1yearincardiacrehabilitationcenterpatients

Ejemplares similares