Ablating Adult Neural Stem Cells Improves Synaptic and Cognitive Functions in Alzheimer Models

Adult neurogenesis is impaired in the hippocampus of patients with Alzheimer disease (AD) as well as AD models. However, it is far from clear how modulating adult neurogenesis affects AD neuropathology. We confirm that adult hippocampal neurogenesis is impaired in two AD models. Surprisingly, howeve...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqin, Mei, Yufei, He, Yang, Wang, Dongpi, Wang, Jing, Wei, Xiaojie, Yang, Enlu, Zhou, Dongming, Shen, Haowei, Peng, Guoping, Shu, Qiang, Li, Xuekun, Luo, Benyan, Zhou, Yudong, Sun, Binggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897582/
https://www.ncbi.nlm.nih.gov/pubmed/33382977
http://dx.doi.org/10.1016/j.stemcr.2020.12.003

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