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Heterozygous P32/C1QBP/HABP1 Polymorphism rs56014026 Reduces Mitochondrial Oxidative Phosphorylation and Is Expressed in Low-grade Colorectal Carcinomas

Rapid proliferation of cancer cells is enabled by favoring aerobic glycolysis over mitochondrial oxidative phosphorylation (OXPHOS). P32 (C1QBP/gC1qR) is essential for mitochondrial protein translation and thus indispensable for OXPHOS activity. It is ubiquitously expressed and directed to the mitoc...

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Detalles Bibliográficos
Autores principales:	Raschdorf, Annika, Sünderhauf, Annika, Skibbe, Kerstin, Ghebrehiwet, Berhane, Peerschke, Ellinor I., Sina, Christian, Derer, Stefanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897657/ https://www.ncbi.nlm.nih.gov/pubmed/33628739 http://dx.doi.org/10.3389/fonc.2020.631592

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