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IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models

Interleukin 15 (IL-15) has been evaluated as a potential treatment for solid tumors in clinical trials, but the effectiveness of systemic IL-15 administration as a monotherapy has not been realized. IL-15 receptor alpha (IL-15Rα) can stabilize IL-15 and enhance its bioactivity. The goal of this stud...

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Detalles Bibliográficos
Autores principales:	Guo, Siqi, Smeltz, Ronald B., Nanajian, Anthony, Heller, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897681/ https://www.ncbi.nlm.nih.gov/pubmed/33628206 http://dx.doi.org/10.3389/fimmu.2020.614667

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