Cortical axonal loss is associated with both gray matter demyelination and white matter tract pathology in progressive multiple sclerosis: Evidence from a combined MRI-histopathology study

BACKGROUND: Neuroaxonal degeneration is one of the hallmarks of clinical deterioration in progressive multiple sclerosis (PMS). OBJECTIVE: To elucidate the association between neuroaxonal degeneration and both local cortical and connected white matter (WM) tract pathology in PMS. METHODS: Post-morte...

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Detalles Bibliográficos
Autores principales: Kiljan, Svenja, Preziosa, Paolo, Jonkman, Laura E, van de Berg, Wilma DJ, Twisk, Jos, Pouwels, Petra JW, Schenk, Geert J, Rocca, Maria A, Filippi, Massimo, Geurts, Jeroen JG, Steenwijk, Martijn D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897796/
https://www.ncbi.nlm.nih.gov/pubmed/32390507
http://dx.doi.org/10.1177/1352458520918978

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