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Computational modeling of stem and progenitor cell kinetics identifies plausible hematopoietic lineage hierarchies

Classically, hematopoietic stem cell (HSC) differentiation is assumed to occur via progenitor compartments of decreasing plasticity and increasing maturity in a specific, hierarchical manner. The classical hierarchy has been challenged in the past by alternative differentiation pathways. We abstract...

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Detalles Bibliográficos
Autores principales:	Bast, Lisa, Buck, Michèle C., Hecker, Judith S., Oostendorp, Robert A.J., Götze, Katharina S., Marr, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897991/ https://www.ncbi.nlm.nih.gov/pubmed/33665548 http://dx.doi.org/10.1016/j.isci.2021.102120

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