High levels of gut-homing immunoglobulin A(+) B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients

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BACKGROUND: Immunoglobulin A nephropathy (IgAN) is the most frequent primary glomerulonephritis. The role of the microbiota and mucosal immunity in the pathogenesis of IgAN remains a key element. To date, the hypothetical relationship between commensal bacteria, elevated tumour necrosis factor (TNF)...

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Detalles Bibliográficos
Autores principales: Sallustio, Fabio, Curci, Claudia, Chaoul, Nada, Fontò, Giulia, Lauriero, Gabriella, Picerno, Angela, Divella, Chiara, Di Leo, Vincenzo, De Angelis, Maria, Ben Mkaddem, Sanae, Macchia, Luigi, Gallone, Anna, Monteiro, Renato C, Pesce, Francesco, Gesualdo, Loreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898021/
https://www.ncbi.nlm.nih.gov/pubmed/33200215
http://dx.doi.org/10.1093/ndt/gfaa264

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