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Loss of RNF43 Function Contributes to Gastric Carcinogenesis by Impairing DNA Damage Response

BACKGROUND & AIMS: RING finger protein 43 (RNF43) is a tumor suppressor that frequently is mutated in gastric tumors. The link between RNF43 and modulation of Wingless-related integration site (WNT) signaling has not been shown clearly in the stomach. Because mutations in RNF43 are highly enrich...

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Detalles Bibliográficos
Autores principales:	Neumeyer, Victoria, Brutau-Abia, Anna, Allgäuer, Michael, Pfarr, Nicole, Weichert, Wilko, Falkeis-Veits, Christina, Kremmer, Elisabeth, Vieth, Michael, Gerhard, Markus, Mejías-Luque, Raquel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898035/ https://www.ncbi.nlm.nih.gov/pubmed/33188943 http://dx.doi.org/10.1016/j.jcmgh.2020.11.005

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