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Therapeutic Effect of Idebenone on Rats with Vascular Dementia via the MicroRNA-216a/RSK2/NF-κB Axis

BACKGROUND: Vascular dementia (VD) is a brain disease featured by cognitive impairment and cerebrovascular pathologies. Idebenone can treat neurodegenerative diseases. This study evaluated the mechanism of Idebenone in VD. METHODS: The VD rat model was established by permanent occlusion of bilateral...

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Detalles Bibliográficos
Autores principales:	Qian, Xudong, Xu, Qianqian, Li, Guoyun, Bu, Yi, Sun, Fan, Zhang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898207/ https://www.ncbi.nlm.nih.gov/pubmed/33628024 http://dx.doi.org/10.2147/NDT.S293614

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