Deconvolution of Complex DNA Repair (DECODR): Establishing a Novel Deconvolution Algorithm for Comprehensive Analysis of CRISPR-Edited Sanger Sequencing Data

During CRISPR-directed gene editing, multiple gene repair mechanisms interact to produce a wide and largely unpredictable variety of sequence changes across an edited population of cells. Shortcomings inherent to previously available proposal-based insertion and deletion (indel) analysis software ne...

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Detalles Bibliográficos
Autores principales: Bloh, Kevin, Kanchana, Rohan, Bialk, Pawel, Banas, Kelly, Zhang, Zugui, Yoo, Byung-Chun, Kmiec, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898406/
https://www.ncbi.nlm.nih.gov/pubmed/33571043
http://dx.doi.org/10.1089/crispr.2020.0022

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