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Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease

BACKGROUND: High-density oligomers of the prion protein (HDPs) have previously been identified in brain tissues of patients with rapidly progressive Alzheimer’s disease (rpAD). The current investigation aims at identifying interacting partners of HDPs in the rpAD brains to unravel the pathological i...

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Detalles Bibliográficos
Autores principales: Shafiq, Mohsin, Zafar, Saima, Younas, Neelam, Noor, Aneeqa, Puig, Berta, Altmeppen, Hermann Clemens, Schmitz, Matthias, Matschke, Jakob, Ferrer, Isidre, Glatzel, Markus, Zerr, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898440/
https://www.ncbi.nlm.nih.gov/pubmed/33618749
http://dx.doi.org/10.1186/s13024-021-00422-x