L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness

BACKGROUND: Metastasis is the predominant cause for cancer morbidity and mortality accounting for approximatively 90% of cancer deaths. The actin-bundling protein L-plastin has been proposed as a metastatic marker and phosphorylation on its residue Ser5 is known to increase its actin-bundling activi...

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Detalles Bibliográficos
Autores principales: Machado, Raquel A. C., Stojevski, Dunja, De Landtsheer, Sébastien, Lucarelli, Philippe, Baron, Alexandre, Sauter, Thomas, Schaffner-Reckinger, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898450/
https://www.ncbi.nlm.nih.gov/pubmed/33618712
http://dx.doi.org/10.1186/s12964-021-00710-5

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