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Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration
Glioblastoma (GBM) is the most lethal primary brain tumor characterized by significant cellular heterogeneity, namely tumor cells, including GBM stem-like cells (GSCs) and differentiated GBM cells (DGCs), and non-tumor cells such as endothelial cells, vascular pericytes, macrophages, and other types...
Autores principales: | Uneda, Atsuhito, Kurozumi, Kazuhiko, Fujimura, Atsushi, Fujii, Kentaro, Ishida, Joji, Shimazu, Yosuke, Otani, Yoshihiro, Tomita, Yusuke, Hattori, Yasuhiko, Matsumoto, Yuji, Tsuboi, Nobushige, Makino, Keigo, Hirano, Shuichiro, Kamiya, Atsunori, Date, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898455/ https://www.ncbi.nlm.nih.gov/pubmed/33618763 http://dx.doi.org/10.1186/s40478-021-01124-7 |
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