Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion

BACKGROUND: Multimerin 1 (human: MMRN1, mouse: Mmrn1) is a homopolymeric, adhesive, platelet and endothelial protein that binds to von Willebrand factor and enhances platelet adhesion to fibrillar collagen ex vivo. OBJECTIVES: To examine the impact of Mmrn1 deficiency on platelet adhesive function,...

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Detalles Bibliográficos
Autores principales: Leatherdale, Alexander, Parker, D’Andra, Tasneem, Subia, Wang, Yiming, Bihan, Dominique, Bonna, Arkadiusz, Hamaia, Samir W., Gross, Peter L., Ni, Heyu, Doble, Bradley W., Lillicrap, David, Farndale, Richard W., Hayward, Catherine P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
PLATELETS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898486/
https://www.ncbi.nlm.nih.gov/pubmed/33179420
http://dx.doi.org/10.1111/jth.15171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898486/
https://www.ncbi.nlm.nih.gov/pubmed/33179420
http://dx.doi.org/10.1111/jth.15171

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