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A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging
PURPOSE: To develop and evaluate a fast respiratory navigator (fastNAV) for cardiac MR perfusion imaging with subject‐specific prospective slice tracking. METHODS: A fastNAV was developed for dynamic contrast‐enhanced cardiac MR perfusion imaging by combining spatially nonselective saturation with s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898590/ https://www.ncbi.nlm.nih.gov/pubmed/33270946 http://dx.doi.org/10.1002/mrm.28617 |
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author | Mooiweer, Ronald Neji, Radhouene McElroy, Sarah Nazir, Muhummad Sohaib Razavi, Reza Chiribiri, Amedeo Roujol, Sébastien |
author_facet | Mooiweer, Ronald Neji, Radhouene McElroy, Sarah Nazir, Muhummad Sohaib Razavi, Reza Chiribiri, Amedeo Roujol, Sébastien |
author_sort | Mooiweer, Ronald |
collection | PubMed |
description | PURPOSE: To develop and evaluate a fast respiratory navigator (fastNAV) for cardiac MR perfusion imaging with subject‐specific prospective slice tracking. METHODS: A fastNAV was developed for dynamic contrast‐enhanced cardiac MR perfusion imaging by combining spatially nonselective saturation with slice‐selective tip‐up and slice‐selective excitation pulses. The excitation slice was angulated from the tip‐up slice in the transverse plane to overlap only in the right hemidiaphragm for suppression of signal outside the right hemidiaphragm. A calibration scan was developed to enable the estimation of subject‐specific tracking factors. Perfusion imaging using subject‐specific fastNAV‐based slice tracking was then compared to a conventional sequence (ie, without slice tracking) in 10 patients under free‐breathing conditions. Respiratory motion in perfusion images was quantitatively assessed by measuring the average overlap of the left ventricle across images (avDice, 0:no overlap/1:perfect overlap) and the average displacement of the center of mass of the left ventricle (avCoM). Image quality was subjectively assessed using a 4‐point scoring system (1: poor, 4: excellent). RESULTS: The fastNAV calibration was successfully performed in all subjects (average tracking factor of 0.46 ± 0.13, R = 0.94 ± 0.03). Prospective motion correction using fastNAV led to higher avDice (0.94 ± 0.02 vs. 0.90 ± 0.03, P < .001) and reduced avCoM (4.03 ± 0.84 vs. 5.22 ± 1.22, P < .001). There were no statistically significant differences between the 2 sequences in terms of image quality (both sequences: median = 3 and interquartile range = 3‐4, P = 1). CONCLUSION: fastNAV enables fast and robust right hemidiaphragm motion tracking in a perfusion sequence. In combination with subject‐specific slice tracking, fastNAV reduces the effect of respiratory motion during free‐breathing cardiac MR perfusion imaging. |
format | Online Article Text |
id | pubmed-7898590 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78985902021-03-03 A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging Mooiweer, Ronald Neji, Radhouene McElroy, Sarah Nazir, Muhummad Sohaib Razavi, Reza Chiribiri, Amedeo Roujol, Sébastien Magn Reson Med Full Papers—Imaging Methodology PURPOSE: To develop and evaluate a fast respiratory navigator (fastNAV) for cardiac MR perfusion imaging with subject‐specific prospective slice tracking. METHODS: A fastNAV was developed for dynamic contrast‐enhanced cardiac MR perfusion imaging by combining spatially nonselective saturation with slice‐selective tip‐up and slice‐selective excitation pulses. The excitation slice was angulated from the tip‐up slice in the transverse plane to overlap only in the right hemidiaphragm for suppression of signal outside the right hemidiaphragm. A calibration scan was developed to enable the estimation of subject‐specific tracking factors. Perfusion imaging using subject‐specific fastNAV‐based slice tracking was then compared to a conventional sequence (ie, without slice tracking) in 10 patients under free‐breathing conditions. Respiratory motion in perfusion images was quantitatively assessed by measuring the average overlap of the left ventricle across images (avDice, 0:no overlap/1:perfect overlap) and the average displacement of the center of mass of the left ventricle (avCoM). Image quality was subjectively assessed using a 4‐point scoring system (1: poor, 4: excellent). RESULTS: The fastNAV calibration was successfully performed in all subjects (average tracking factor of 0.46 ± 0.13, R = 0.94 ± 0.03). Prospective motion correction using fastNAV led to higher avDice (0.94 ± 0.02 vs. 0.90 ± 0.03, P < .001) and reduced avCoM (4.03 ± 0.84 vs. 5.22 ± 1.22, P < .001). There were no statistically significant differences between the 2 sequences in terms of image quality (both sequences: median = 3 and interquartile range = 3‐4, P = 1). CONCLUSION: fastNAV enables fast and robust right hemidiaphragm motion tracking in a perfusion sequence. In combination with subject‐specific slice tracking, fastNAV reduces the effect of respiratory motion during free‐breathing cardiac MR perfusion imaging. John Wiley and Sons Inc. 2020-12-03 2021-05 /pmc/articles/PMC7898590/ /pubmed/33270946 http://dx.doi.org/10.1002/mrm.28617 Text en © 2020 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Full Papers—Imaging Methodology Mooiweer, Ronald Neji, Radhouene McElroy, Sarah Nazir, Muhummad Sohaib Razavi, Reza Chiribiri, Amedeo Roujol, Sébastien A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
title | A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
title_full | A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
title_fullStr | A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
title_full_unstemmed | A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
title_short | A fast navigator (fastNAV) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
title_sort | fast navigator (fastnav) for prospective respiratory motion correction in first‐pass myocardial perfusion imaging |
topic | Full Papers—Imaging Methodology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898590/ https://www.ncbi.nlm.nih.gov/pubmed/33270946 http://dx.doi.org/10.1002/mrm.28617 |
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