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Synthesis and Evaluation of Non‐Hydrolyzable Phospho‐Lysine Peptide Mimics

The intrinsic lability of the phosphoramidate P−N bond in phosphorylated histidine (pHis), arginine (pHis) and lysine (pLys) residues is a significant challenge for the investigation of these post‐translational modifications (PTMs), which gained attention rather recently. While stable mimics of pHis...

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Detalles Bibliográficos
Autores principales: Hauser, Anett, Poulou, Eleftheria, Müller, Fabian, Schmieder, Peter, Hackenberger, Christian P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898648/
https://www.ncbi.nlm.nih.gov/pubmed/32986895
http://dx.doi.org/10.1002/chem.202003947