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Mechanical valve replacement without anticoagulation: a case report

BACKGROUND: For patients who undergo mechanical valve replacement, the greatest disadvantage is that they require long-term or permanent use of anticoagulant therapy to prevent thromboembolism. To date, mechanical valve replacement without anticoagulation has been published in the literature. CASE S...

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Detalles Bibliográficos
Autores principales: Wang, Yapeng, Lin, Min, Ge, Shenglin, Feng, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898660/
https://www.ncbi.nlm.nih.gov/pubmed/33644653
http://dx.doi.org/10.1093/ehjcr/ytaa566
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author Wang, Yapeng
Lin, Min
Ge, Shenglin
Feng, Junbo
author_facet Wang, Yapeng
Lin, Min
Ge, Shenglin
Feng, Junbo
author_sort Wang, Yapeng
collection PubMed
description BACKGROUND: For patients who undergo mechanical valve replacement, the greatest disadvantage is that they require long-term or permanent use of anticoagulant therapy to prevent thromboembolism. To date, mechanical valve replacement without anticoagulation has been published in the literature. CASE SUMMARY: We present the case of a 75-year-old female who underwent mechanical mitral valve replacement (MVR) on mid-June, 2007. However, this patient had not been taking anticoagulant medication since she experienced warfarin overdose in the first month after the operation. She had been well without using any anticoagulation, and there were no complications of the mechanical valve. DISCUSSION: There was no thrombosis for such a long period of time because she suffered from FX deficiency. To the best of our knowledge, she may be the only patient who has been well without any anticoagulation since not taking warfarin 12 years ago.
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spelling pubmed-78986602021-02-25 Mechanical valve replacement without anticoagulation: a case report Wang, Yapeng Lin, Min Ge, Shenglin Feng, Junbo Eur Heart J Case Rep Case Report BACKGROUND: For patients who undergo mechanical valve replacement, the greatest disadvantage is that they require long-term or permanent use of anticoagulant therapy to prevent thromboembolism. To date, mechanical valve replacement without anticoagulation has been published in the literature. CASE SUMMARY: We present the case of a 75-year-old female who underwent mechanical mitral valve replacement (MVR) on mid-June, 2007. However, this patient had not been taking anticoagulant medication since she experienced warfarin overdose in the first month after the operation. She had been well without using any anticoagulation, and there were no complications of the mechanical valve. DISCUSSION: There was no thrombosis for such a long period of time because she suffered from FX deficiency. To the best of our knowledge, she may be the only patient who has been well without any anticoagulation since not taking warfarin 12 years ago. Oxford University Press 2021-01-15 /pmc/articles/PMC7898660/ /pubmed/33644653 http://dx.doi.org/10.1093/ehjcr/ytaa566 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wang, Yapeng
Lin, Min
Ge, Shenglin
Feng, Junbo
Mechanical valve replacement without anticoagulation: a case report
title Mechanical valve replacement without anticoagulation: a case report
title_full Mechanical valve replacement without anticoagulation: a case report
title_fullStr Mechanical valve replacement without anticoagulation: a case report
title_full_unstemmed Mechanical valve replacement without anticoagulation: a case report
title_short Mechanical valve replacement without anticoagulation: a case report
title_sort mechanical valve replacement without anticoagulation: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898660/
https://www.ncbi.nlm.nih.gov/pubmed/33644653
http://dx.doi.org/10.1093/ehjcr/ytaa566
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