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Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition
Alveologenesis is a developmental step involving the expansion of the lung surface area which is essential for gas exchange. The gas exchange process is mediated by alveolar type I (AT1) cells, which are known to be differentiated from alveolar type II (AT2) or bipotent cells. Due to the difficulty...
Autores principales: | Kanagaki, Shuhei, Ikeo, Satoshi, Suezawa, Takahiro, Yamamoto, Yuki, Seki, Masahide, Hirai, Toyohiro, Hagiwara, Masatoshi, Suzuki, Yutaka, Gotoh, Shimpei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898721/ https://www.ncbi.nlm.nih.gov/pubmed/33241896 http://dx.doi.org/10.1002/stem.3302 |
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