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Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments
BACKGROUND: The mu-opioid agonist methadone is administered orally and used in opioid detoxification and in the treatment of moderate-to-severe pain. Acute oral methadone–use and –abuse have been associated with inflammatory and toxic central nervous system (CNS) damage in some cases and cognitive d...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898738/ https://www.ncbi.nlm.nih.gov/pubmed/33618681 http://dx.doi.org/10.1186/s12883-021-02108-9 |