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Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications
BACKGROUND: Acetylcholine (ACh) plays a crucial role in the function of the heart. Recent evidence suggests that cardiomyocytes possess a non-neuronal cholinergic system (NNCS) that comprises of choline acetyltransferase (ChAT), choline transporter 1 (CHT1), vesicular acetylcholine transporter (VACh...
Autores principales: | Saw, Eng Leng, Pearson, James T., Schwenke, Daryl O., Munasinghe, Pujika Emani, Tsuchimochi, Hirotsugu, Rawal, Shruti, Coffey, Sean, Davis, Philip, Bunton, Richard, Van Hout, Isabelle, Kai, Yuko, Williams, Michael J. A., Kakinuma, Yoshihiko, Fronius, Martin, Katare, Rajesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898760/ https://www.ncbi.nlm.nih.gov/pubmed/33618724 http://dx.doi.org/10.1186/s12933-021-01231-8 |
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