Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability

Intratumor heterogeneity of colorectal cancers (CRCs) is manifested both at the genomic and epigenomic levels. Early genetic aberrations in carcinogenesis are clonal and present throughout the tumors, but less is known about the heterogeneity of the epigenetic CpG island methylator phenotype (CIMP)....

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Detalles Bibliográficos
Autores principales: Flatin, Bjørnar T.B., Vedeld, Hege Marie, Pinto, Rita, Langerud, Jonas, Lind, Guro E., Lothe, Ragnhild A., Sveen, Anita, Jeanmougin, Marine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Cancer Genetics and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898891/
https://www.ncbi.nlm.nih.gov/pubmed/33284993
http://dx.doi.org/10.1002/ijc.33425

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