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Dietary saturated fatty acid palmitate promotes cartilage lesions and activates the unfolded protein response pathway in mouse knee joints
Increased intake of dietary saturated fatty acids has been linked to obesity and the development of Osteoarthritis (OA). However, the mechanism by which these fats promote cartilage degradation and the development of OA is not clearly understood. Here, we report the effects of consumption of common...
Autores principales: | Tan, Li, Harper, Lindsey R., Armstrong, Alexandra, Carlson, Cathy S., Yammani, Raghunatha R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899342/ https://www.ncbi.nlm.nih.gov/pubmed/33617553 http://dx.doi.org/10.1371/journal.pone.0247237 |
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