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Dietary saturated fatty acid palmitate promotes cartilage lesions and activates the unfolded protein response pathway in mouse knee joints

Increased intake of dietary saturated fatty acids has been linked to obesity and the development of Osteoarthritis (OA). However, the mechanism by which these fats promote cartilage degradation and the development of OA is not clearly understood. Here, we report the effects of consumption of common...

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Detalles Bibliográficos
Autores principales: Tan, Li, Harper, Lindsey R., Armstrong, Alexandra, Carlson, Cathy S., Yammani, Raghunatha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899342/
https://www.ncbi.nlm.nih.gov/pubmed/33617553
http://dx.doi.org/10.1371/journal.pone.0247237

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