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Genetic variation in surfactant protein-A2 alters responses to ozone

BACKGROUND: Increased exposure to Ozone (O(3)) is associated with adverse health effects in individuals afflicted with respiratory diseases. Surfactant protein-A (SP-A), encoded by SP-A1 and SP-A2, is the largest protein component in pulmonary surfactant and is functionally impaired by O(3)-oxidatio...

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Detalles Bibliográficos
Autores principales: Pederson, William P., Cyphert-Daly, Jaime M., Tighe, Robert M., Que, Loretta G., Ledford, Julie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899376/
https://www.ncbi.nlm.nih.gov/pubmed/33617569
http://dx.doi.org/10.1371/journal.pone.0247504

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