Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

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Rationally designed protein subunit vaccines are being developed for a variety of viruses including influenza, RSV, SARS-CoV-2 and HIV. These vaccines are based on stabilized versions of the primary targets of neutralizing antibodies on the viral surface, namely viral fusion glycoproteins. While the...

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Detalles Bibliográficos
Autores principales: Turner, Hannah L., Andrabi, Raiees, Cottrell, Christopher A., Richey, Sara T., Song, Ge, Callaghan, Sean, Anzanello, Fabio, Moyer, Tyson J., Abraham, Wuhbet, Melo, Mariane, Silva, Murillo, Scaringi, Nicole, Rakasz, Eva G., Sattentau, Quentin, Irvine, Darrell J., Burton, Dennis R., Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899455/
https://www.ncbi.nlm.nih.gov/pubmed/33619491
http://dx.doi.org/10.1101/2021.02.16.431310
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