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Quercetin shortened survival of radio-resistant B-1 cells in vitro and in vivo by restoring miR15a/16 expression
Chronic lymphocytic leukemia (CLL) is a malignancy disease characterized by the expansion of CD5(+) B-1 cells. The NZB mouse model of CLL shows similarities to human CLL, has age-associated increase in malignant B-1 clones and decreased expression of miR-15a/16. It was demonstrated that systemic len...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899548/ https://www.ncbi.nlm.nih.gov/pubmed/33659046 http://dx.doi.org/10.18632/oncotarget.27883 |