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Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2
The effects and mechanisms of folic acid (FA) as a chemopreventive agent for tumorigenesis of hepatocellular carcinoma (HCC) remain unclear. In this study, the QSG-7701, a human normal liver cell line, was cultured in different FA levels (High, Normal or No) for 6 months. Then, the biological charac...
Autores principales: | Zhang, Yin-Ling, Xue, Geng, Miao, Hui, Zhou, Chuan-Chuan, Sun, Shu-Han, Zhang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899549/ https://www.ncbi.nlm.nih.gov/pubmed/33659047 http://dx.doi.org/10.18632/oncotarget.27136 |
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