Cargando…
A critical residue in the α(1)M2–M3 linker regulating mammalian GABA(A) receptor pore gating by diazepam
Benzodiazepines (BZDs) are a class of widely prescribed psychotropic drugs that modulate activity of GABA(A) receptors (GABA(A)Rs), neurotransmitter-gated ion channels critical for synaptic transmission. However, the physical basis of this modulation is poorly understood. We explore the role of an i...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899671/ https://www.ncbi.nlm.nih.gov/pubmed/33591271 http://dx.doi.org/10.7554/eLife.64400 |