Dot1l Aggravates Keratitis Induced by Herpes Simplex Virus Type 1 in Mice via p38 MAPK-Mediated Oxidative Stress

BACKGROUND: Disruptor of telomeric silencing 1-like (Dot1l) plays a vital role in biological processes as a well-known methyltransferase. However, its role in herpes simplex virus type 1- (HSV-1-) infected keratitis remains unclear. METHODS: In vitro and in vivo models were assessed to investigate t...

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Detalles Bibliográficos
Autores principales: Wan, Shanshan, Zhou, Yiwen, Huang, Qiong, Yang, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899779/
https://www.ncbi.nlm.nih.gov/pubmed/33628364
http://dx.doi.org/10.1155/2021/6612689

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