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Osteoclast-derived small extracellular vesicles induce osteogenic differentiation via inhibiting ARHGAP1

Activated osteoclasts release large amounts of small extracellular vesicles (sEVs) during bone remodeling. However, little is known about whether osteoclast-derived sEVs affect surrounding cells. In this study, osteoclasts were generated by stimulating bone marrow macrophages (BMMs) with macrophage...

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Detalles Bibliográficos
Autores principales: Liang, Mengmeng, Yin, Xiaofan, Zhang, Shuai, Ai, Hongbo, Luo, Fei, Xu, Jianzhong, Dou, Ce, Dong, Shiwu, Ma, Qinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900016/
https://www.ncbi.nlm.nih.gov/pubmed/33664997
http://dx.doi.org/10.1016/j.omtn.2021.01.031