Cargando…

Osteoclast-derived small extracellular vesicles induce osteogenic differentiation via inhibiting ARHGAP1

Activated osteoclasts release large amounts of small extracellular vesicles (sEVs) during bone remodeling. However, little is known about whether osteoclast-derived sEVs affect surrounding cells. In this study, osteoclasts were generated by stimulating bone marrow macrophages (BMMs) with macrophage...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Mengmeng, Yin, Xiaofan, Zhang, Shuai, Ai, Hongbo, Luo, Fei, Xu, Jianzhong, Dou, Ce, Dong, Shiwu, Ma, Qinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900016/ https://www.ncbi.nlm.nih.gov/pubmed/33664997 http://dx.doi.org/10.1016/j.omtn.2021.01.031

Ejemplares similares

Small extracellular vesicles deliver osteolytic effectors and mediate cancer‐induced osteolysis in bone metastatic niche
por: Ma, Qinyu, et al.
Publicado: (2021)

Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling
por: Ma, Qinyu, et al.
Publicado: (2021)

Replenishing decoy extracellular vesicles inhibits phenotype remodeling of tissue-resident cells in inflammation-driven arthritis
por: Liang, Mengmeng, et al.
Publicado: (2023)

Reduced osteoclast-derived apoptotic bodies in bone marrow characterizes the pathological progression of osteoporosis
por: Wu, Yutong, et al.
Publicado: (2023)

Osteoclast-derived apoptotic bodies show extended biological effects of parental cell in promoting bone defect healing
por: Ma, Qinyu, et al.
Publicado: (2020)

Osteoclast-derived apoptotic bodies inhibit naive CD8(+) T cell activation via Siglec15, promoting breast cancer secondary metastasis
por: Wu, Yutong, et al.
Publicado: (2023)

Osteoclast-Derived Extracellular Vesicles: Novel Regulators of Osteoclastogenesis and Osteoclast–Osteoblasts Communication in Bone Remodeling
por: Yuan, Feng-Lai, et al.
Publicado: (2018)

Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry
por: Shi, Fan, et al.
Publicado: (2022)

Actin and Actin-Associated Proteins in Extracellular Vesicles Shed by Osteoclasts
por: Holliday, L. Shannon, et al.
Publicado: (2019)

IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis
por: Liang, Mengmeng, et al.
Publicado: (2019)

Uptake of osteoblast-derived extracellular vesicles promotes the differentiation of osteoclasts in the zebrafish scale
por: Kobayashi-Sun, Jingjing, et al.
Publicado: (2020)

Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts
por: Murray, Jonathan B., et al.
Publicado: (2021)

Effects of extracellular vesicles derived from oral bacteria on osteoclast differentiation and activation
por: Kim, Hyun Young, et al.
Publicado: (2022)

Periostin: A Downstream Mediator of EphB4-Induced Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Zhang, Fei, et al.
Publicado: (2016)

Milk-Derived Small Extracellular Vesicles Promote Osteogenic Differentiation and Inhibit Inflammation via microRNA-21
por: Liu, Runyuan, et al.
Publicado: (2023)

p190RhoGAPs, the ARHGAP35- and ARHGAP5-Encoded Proteins, in Health and Disease
por: Héraud, Capucine, et al.
Publicado: (2019)

An osteogenic helioxanthin derivative suppresses the formation of bone-resorbing osteoclasts
por: Amano, Hitoshi, et al.
Publicado: (2019)

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs
por: Wang, Chenglong, et al.
Publicado: (2022)

Evaluation of the cargo contents and potential role of extracellular vesicles in osteoporosis
por: Xu, Jifeng, et al.
Publicado: (2021)

Drug Delivery: Graphene‐Based MicroRNA Transfection Blocks Preosteoclast Fusion to Increase Bone Formation and Vascularization (Adv. Sci. 2/2018)
por: Dou, Ce, et al.
Publicado: (2018)

Graphene‐Based MicroRNA Transfection Blocks Preosteoclast Fusion to Increase Bone Formation and Vascularization
por: Dou, Ce, et al.
Publicado: (2017)

Graphene‐Based MicroRNA Transfection Blocks Preosteoclast Fusion to Increase Bone Formation and Vascularization
por: Dou, Ce, et al.
Publicado: (2021)

Sialylation of TLR2 initiates osteoclast fusion
por: Dou, Ce, et al.
Publicado: (2022)

Mechanism of cargo sorting into small extracellular vesicles
por: Chen, Yiwen, et al.
Publicado: (2021)

Small extracellular vesicles in cancer
por: Abhange, Komal, et al.
Publicado: (2021)

Impact of cigarette smoke on osteogenic and osteoclast signaling in middle palatal suture
por: Arnez, Maya Fernanda Manfrin, et al.
Publicado: (2022)

Inhibition of Osteoclast Differentiation and Promotion of Osteogenic Formation by Wolfiporia extensa Mycelium
por: Son, Tae Hyun, et al.
Publicado: (2023)

Bone-targeted pH-responsive cerium nanoparticles for anabolic therapy in osteoporosis
por: Dou, Ce, et al.
Publicado: (2021)

Extracellular Vesicle microRNAs Contribute to the Osteogenic Inhibition of Mesenchymal Stem Cells in Multiple Myeloma
por: Raimondo, Stefania, et al.
Publicado: (2020)

Curcumin-primed periodontal ligament stem cells-derived extracellular vesicles improve osteogenic ability through the Wnt/β-catenin pathway
por: Lan, Qian, et al.
Publicado: (2023)

Bimodal antagonism of PKA signalling by ARHGAP36
por: Eccles, Rebecca L., et al.
Publicado: (2016)

Hematopoietic defects in response to reduced Arhgap21
por: Xavier-Ferrucio, Juliana, et al.
Publicado: (2017)

Exosomal lipid PI4P regulates small extracellular vesicle secretion by modulating intraluminal vesicle formation
por: Jin, Xue, et al.
Publicado: (2023)

Small Extracellular Vesicles in Transplant Rejection
por: Gołębiewska, Justyna E., et al.
Publicado: (2021)

Extracellular matrix stiffness mediates uterine repair via the Rap1a/ARHGAP35/RhoA/F-actin/YAP axis
por: Zhang, Tao, et al.
Publicado: (2023)

Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers
por: Naeimzadeh, Y., et al.
Publicado: (2023)

Clinical Application of Small Extracellular Vesicles in Gynecologic Malignancy Treatments
por: Zheng, Fei, et al.
Publicado: (2023)

[Corrigendum] Anti‑osteoporotic effects of tetramethylpyrazine via promoting osteogenic differentiation and inhibiting osteoclast formation
por: Wang, Long, et al.
Publicado: (2023)

Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss
por: Singleton, Quante, et al.
Publicado: (2019)

Osteoclast-derived extracellular vesicles are implicated in sensory neurons sprouting through the activation of epidermal growth factor signaling
por: Neto, Estrela, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_plt4sp8rv7jvae9nvio2hkkhg2