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Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis

Melanoma is the most lethal skin malignancy, driven by genetic and epigenetic alterations in the complex tumour microenvironment. While large-scale molecular profiling of melanoma has identified molecular signatures associated with melanoma progression, comprehensive systems-level modeling remains e...

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Detalles Bibliográficos
Autores principales: Song, Won-Min, Agrawal, Praveen, Von Itter, Richard, Fontanals-Cirera, Barbara, Wang, Minghui, Zhou, Xianxiao, Mahal, Lara K., Hernando, Eva, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900178/
https://www.ncbi.nlm.nih.gov/pubmed/33619278
http://dx.doi.org/10.1038/s41467-021-21457-0