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Causal role for sleep-dependent reactivation of learning-activated sensory ensembles for fear memory consolidation
Learning-activated engram neurons play a critical role in memory recall. An untested hypothesis is that these same neurons play an instructive role in offline memory consolidation. Here we show that a visually-cued fear memory is consolidated during post-conditioning sleep in mice. We then use TRAP...
Autores principales: | Clawson, Brittany C., Pickup, Emily J., Ensing, Amy, Geneseo, Laura, Shaver, James, Gonzalez-Amoretti, John, Zhao, Meiling, York, A. Kane, Kuhn, Femke Roig, Swift, Kevin, Martinez, Jessy D., Wang, Lijing, Jiang, Sha, Aton, Sara J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900186/ https://www.ncbi.nlm.nih.gov/pubmed/33619256 http://dx.doi.org/10.1038/s41467-021-21471-2 |
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