Cargando…
Emodin Interferes With AKT1-Mediated DNA Damage and Decreases Resistance of Breast Cancer Cells to Doxorubicin
Doxorubicin (DOX) is a cytotoxic drug used for the treatment of breast cancer (BC). However, the rapid emergence of resistance toward doxorubicin threatens its clinical application, thus the need for combination therapy. Here, we interrogate the role of Emodin, a chemical compound with tumor inhibit...
Autores principales: | Li, Bo, Zhao, Xin, Zhang, Lei, Cheng, Wen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900193/ https://www.ncbi.nlm.nih.gov/pubmed/33634018 http://dx.doi.org/10.3389/fonc.2020.588533 |
Ejemplares similares
-
Corrigendum: Emodin Interferes With AKT1-Mediated DNA Damage and Decreases Resistance of Breast Cancer Cells to Doxorubicin
por: Li, Bo, et al.
Publicado: (2021) -
Isoalantolactone Enhances the Antitumor Activity of Doxorubicin by Inducing Reactive Oxygen Species and DNA Damage
por: Wu, Fengjiao, et al.
Publicado: (2022) -
Pictilisib Enhances the Antitumor Effect of Doxorubicin and Prevents Tumor-Mediated Bone Destruction by Blockade of PI3K/AKT Pathway
por: Liang, Chao, et al.
Publicado: (2021) -
Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways
por: Roy, Gaurab, et al.
Publicado: (2019) -
Emodin Interferes With Nitroglycerin-Induced Migraine in Rats Through CGMP-PKG Pathway
por: Sun, Shuding, et al.
Publicado: (2021)