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Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women

Mosaicism in blood varies with age, and cross-sectional studies indicate that for women, skewness of X-chromosomal mosaicism increases with age. This pattern could, however, also be due to less X-inactivation in more recent birth cohorts. Skewed X-chromosome inactivation was here measured longitudin...

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Detalles Bibliográficos
Autores principales:	Mengel-From, Jonas, Lindahl-Jacobsen, Rune, Nygaard, Marianne, Soerensen, Mette, Ørstavik, Karen Helene, Hertz, Jens Michael, Andersen-Ranberg, Karen, Tan, Qihua, Christensen, Kaare
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900237/ https://www.ncbi.nlm.nih.gov/pubmed/33619309 http://dx.doi.org/10.1038/s41598-021-83702-2

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