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Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering
Single-cell transcriptomics suffer from sensitivity limits that restrict low abundance transcript identification, affects clustering and can hamper downstream analyses. Here, we describe Constellation sequencing (Constellation-Seq), a molecular transcriptome filter that delivers two orders of magnit...
Autores principales: | Vallejo, Andres F., Davies, James, Grover, Amit, Tsai, Ching-Hsuan, Jepras, Robert, Polak, Marta E., West, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900351/ https://www.ncbi.nlm.nih.gov/pubmed/33665566 http://dx.doi.org/10.1016/j.isci.2021.102147 |
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