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Conserved nicotine-activated neuroprotective pathways involve mitochondrial stress
Tobacco smoking is a risk factor for several human diseases. Conversely, smoking also reduces the prevalence of Parkinson’s disease, whose hallmark is degeneration of substantia nigra dopaminergic neurons (DNs). We use C. elegans as a model to investigate whether tobacco-derived nicotine activates n...
Autores principales: | Nourse, J. Brucker, Harshefi, Gilad, Marom, Adi, Karmi, Abdelrahaman, Cohen Ben-Ami, Hagit, Caldwell, Kim A., Caldwell, Guy A., Treinin, Millet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900352/ https://www.ncbi.nlm.nih.gov/pubmed/33665559 http://dx.doi.org/10.1016/j.isci.2021.102140 |
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