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Change in the Single Amino Acid Site 83 in Rabies Virus Glycoprotein Enhances the BBB Permeability and Reduces Viral Pathogenicity

Lab-attenuated rabies virus (RABV) is a highly cellular adaptation and less pathogenic than wild-type RABV. However, the molecular mechanisms that regulate the cellular adaptation and pathogenicity remain obscure. In this work, we isolated a wild-type RABV (CNIM1701) from a rabid bovine in northern...

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Detalles Bibliográficos
Autores principales:	Li, Chunfu, Wang, Yongzhi, Liu, Huiting, Zhang, Xinghua, Baolige, Dalai, Zhao, Shihua, Hu, Wei, Yang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900495/ https://www.ncbi.nlm.nih.gov/pubmed/33634109 http://dx.doi.org/10.3389/fcell.2020.632957

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