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A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development

Paracrine signaling in the tissue microenvironment is a central mediator of morphogenesis, and modeling this dynamic intercellular activity in vitro is critical to understanding normal and abnormal development. For example, Sonic Hedgehog (Shh) signaling is a conserved mechanism involved in multiple...

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Detalles Bibliográficos
Autores principales: Johnson, Brian P., Vitek, Ross A., Morgan, Molly M., Fink, Dustin M., Beames, Tyler G., Geiger, Peter G., Beebe, David J., Lipinski, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900501/
https://www.ncbi.nlm.nih.gov/pubmed/33634122
http://dx.doi.org/10.3389/fcell.2021.621442

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