The Cancer/Testis Antigen Gene VCX2 Is Rarely Expressed in Malignancies but Can Be Epigenetically Activated Using DNA Methyltransferase and Histone Deacetylase Inhibitors

Identification of novel tumor-specific targets is important for the future development of immunotherapeutic strategies using genetically engineered T cells or vaccines. In this study, we characterized the expression of VCX2, a member of the VCX/Y cancer/testis antigen family, in a large panel of nor...

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Detalles Bibliográficos
Autores principales: Jakobsen, Mie K., Traynor, Sofie, Stæhr, Mette, Duijf, Pascal G., Nielsen, Aaraby Y., Terp, Mikkel G., Pedersen, Christina B., Guldberg, Per, Ditzel, Henrik J., Gjerstorff, Morten F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900521/
https://www.ncbi.nlm.nih.gov/pubmed/33634013
http://dx.doi.org/10.3389/fonc.2020.584024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900521/
https://www.ncbi.nlm.nih.gov/pubmed/33634013
http://dx.doi.org/10.3389/fonc.2020.584024

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