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The Complexity of the cGAS-STING Pathway in CNS Pathologies
Neuroinflammation driven by type-I interferons in the CNS is well established to exacerbate the progression of many CNS pathologies both acute and chronic. The role of adaptor protein Stimulator of Interferon Genes (STING) is increasingly appreciated to instigate type-I IFN-mediated neuroinflammatio...
Autores principales: | Fryer, Amelia L., Abdullah, Amar, Taylor, Juliet M., Crack, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900568/ https://www.ncbi.nlm.nih.gov/pubmed/33633536 http://dx.doi.org/10.3389/fnins.2021.621501 |
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