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Lithium modulates miR‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation

Lithium is neuroprotective in preclinical stroke models. In addition to that, poststroke neuroregeneration is stimulated upon transplantation of mesenchymal stem cells (MSCs). Preconditioning of MSCs with lithium further enhances the neuroregenerative potential of MSCs, which act by secreting extrac...

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Detalles Bibliográficos
Autores principales: Haupt, Matteo, Zheng, Xuan, Kuang, Yaoyun, Lieschke, Simone, Janssen, Lisa, Bosche, Bert, Jin, Fengyan, Hein, Katharina, Kilic, Ertugrul, Venkataramani, Vivek, Hermann, Dirk M., Bähr, Mathias, Doeppner, Thorsten R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900596/
https://www.ncbi.nlm.nih.gov/pubmed/33146943
http://dx.doi.org/10.1002/sctm.20-0086