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A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China

Epidemic forecasting provides an opportunity to predict geographic disease spread and counts when an outbreak occurs and plays a key role in preventing or controlling their adverse impact. However, conventional prediction models based on complex mathematical modelling rely on the estimation of model...

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Autores principales: Shang, Chenjing, Yang, Yang, Chen, Gui-Ying, Shang, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900669/
https://www.ncbi.nlm.nih.gov/pubmed/33563354
http://dx.doi.org/10.1017/S0950268821000339
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author Shang, Chenjing
Yang, Yang
Chen, Gui-Ying
Shang, Xiao-Dong
author_facet Shang, Chenjing
Yang, Yang
Chen, Gui-Ying
Shang, Xiao-Dong
author_sort Shang, Chenjing
collection PubMed
description Epidemic forecasting provides an opportunity to predict geographic disease spread and counts when an outbreak occurs and plays a key role in preventing or controlling their adverse impact. However, conventional prediction models based on complex mathematical modelling rely on the estimation of model parameters, which yields unreliable and unsustainable results. Herein, we proposed a simple model for predicting the epidemic transmission dynamics based on nonlinear regression of the epidemic growth rate and iterative methods, which is applicable to the progression of the COVID-19 outbreak under the strict control measures of the Chinese government. Our model yields reliable and accurate results as confirmed by the available data: we predicted that the total number of infections in mainland China would be 91 253, and the maximum number of beds required for hospitalised patients would be 62 794. We inferred that the inflection point (when the growth rate turns from positive to negative) of the epidemic across China would be mid-February, and the end of the epidemic would be in late March. This model is expected to contribute to resource allocation and planning in the health sector while providing a theoretical basis for governments to respond to future global health crises or epidemics.
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spelling pubmed-79006692021-02-23 A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China Shang, Chenjing Yang, Yang Chen, Gui-Ying Shang, Xiao-Dong Epidemiol Infect Original Paper Epidemic forecasting provides an opportunity to predict geographic disease spread and counts when an outbreak occurs and plays a key role in preventing or controlling their adverse impact. However, conventional prediction models based on complex mathematical modelling rely on the estimation of model parameters, which yields unreliable and unsustainable results. Herein, we proposed a simple model for predicting the epidemic transmission dynamics based on nonlinear regression of the epidemic growth rate and iterative methods, which is applicable to the progression of the COVID-19 outbreak under the strict control measures of the Chinese government. Our model yields reliable and accurate results as confirmed by the available data: we predicted that the total number of infections in mainland China would be 91 253, and the maximum number of beds required for hospitalised patients would be 62 794. We inferred that the inflection point (when the growth rate turns from positive to negative) of the epidemic across China would be mid-February, and the end of the epidemic would be in late March. This model is expected to contribute to resource allocation and planning in the health sector while providing a theoretical basis for governments to respond to future global health crises or epidemics. Cambridge University Press 2021-02-10 /pmc/articles/PMC7900669/ /pubmed/33563354 http://dx.doi.org/10.1017/S0950268821000339 Text en © The Author(s) 2021 http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Shang, Chenjing
Yang, Yang
Chen, Gui-Ying
Shang, Xiao-Dong
A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China
title A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China
title_full A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China
title_fullStr A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China
title_full_unstemmed A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China
title_short A simple transmission dynamics model for predicting the evolution of COVID-19 under control measures in China
title_sort simple transmission dynamics model for predicting the evolution of covid-19 under control measures in china
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900669/
https://www.ncbi.nlm.nih.gov/pubmed/33563354
http://dx.doi.org/10.1017/S0950268821000339
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