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Use of a molecular beacon based fluorescent method for assaying uracil DNA glycosylase (Ung) activity and inhibitor screening

Uracil DNA glycosylases are an important class of enzymes that hydrolyze the N-glycosidic bond between the uracil base and the deoxyribose sugar to initiate uracil excision repair. Uracil may arise in DNA either because of its direct incorporation (against A in the template) or because of cytosine d...

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Detalles Bibliográficos
Autores principales:	Mehta, Avani, Raj, Prateek, Sundriyal, Sandeep, Gopal, Balasubramanian, Varshney, Umesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900708/ https://www.ncbi.nlm.nih.gov/pubmed/33665381 http://dx.doi.org/10.1016/j.bbrep.2021.100954

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