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Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)

PURPOSE: To examine the contribution of pigment epithelium-derived factor receptor (PEDF-R) to the phagocytosis process. Previously, we identified PEDF-R, the protein encoded by the PNPLA2 gene, as a phospholipase A2 in the retinal pigment epithelium (RPE). During phagocytosis, RPE cells ingest abun...

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Detalles Bibliográficos
Autores principales:	Bullock, Jeanee, Polato, Federica, Abu-Asab, Mones, Bernardo-Colón, Alexandra, Aflaki, Elma, Agbaga, Martin-Paul, Becerra, S. Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900850/ https://www.ncbi.nlm.nih.gov/pubmed/33605986 http://dx.doi.org/10.1167/iovs.62.2.30

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