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Antibody‐dependent enhancement (ADE) of dengue virus: Identification of the key amino acid that is vital in DENV vaccine research

BACKGROUND: The antibody‐dependent enhancement (ADE) of dengue virus (DENV) has critically restricted vaccine development. Prior research suggested pr4 as the probable ADE epitope of DENV. METHODS: Chimeric DENV was constructed by replacing the DENV pr4 gene with the corresponding Japanese encephali...

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Detalles Bibliográficos
Autores principales:	Cui, Guohui, Si, Lulu, Wang, Ying, Zhou, Junmei, Yan, Huijun, Jiang, Lifang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900978/ https://www.ncbi.nlm.nih.gov/pubmed/33217097 http://dx.doi.org/10.1002/jgm.3297

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