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Prime Editing Guide RNA Design Automation Using PINE-CONE
[Image: see text] CRISPR-based technologies are paramount in genome engineering and synthetic biology. Prime editing (PE) is a technology capable of installing genomic edits without double-stranded DNA breaks (DSBs) or donor DNA. Prime editing guide RNAs (pegRNAs) simultaneously encode both guide an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901017/ https://www.ncbi.nlm.nih.gov/pubmed/33464043 http://dx.doi.org/10.1021/acssynbio.0c00445 |