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Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor

Microglia are the resident phagocytes of the central nervous system, and microglial activation is considered to play an important role in the pathogenesis of neurodegenerative diseases. Recent studies with single-cell RNA analysis of CNS cells in Alzheimer’s disease and diverse other neurodegenerati...

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Detalles Bibliográficos
Autores principales: Maeda, Jun, Minamihisamatsu, Takeharu, Shimojo, Masafumi, Zhou, Xiaoyun, Ono, Maiko, Matsuba, Yukio, Ji, Bin, Ishii, Hideki, Ogawa, Masanao, Akatsu, Hiroyasu, Kaneda, Daita, Hashizume, Yoshio, Robinson, John L, Lee, Virginia M -Y, Saito, Takashi, Saido, Takaomi C, Trojanowski, John Q, Zhang, Ming-Rong, Suhara, Tetsuya, Higuchi, Makoto, Sahara, Naruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901060/
https://www.ncbi.nlm.nih.gov/pubmed/33644757
http://dx.doi.org/10.1093/braincomms/fcab011