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Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor
Microglia are the resident phagocytes of the central nervous system, and microglial activation is considered to play an important role in the pathogenesis of neurodegenerative diseases. Recent studies with single-cell RNA analysis of CNS cells in Alzheimer’s disease and diverse other neurodegenerati...
Autores principales: | Maeda, Jun, Minamihisamatsu, Takeharu, Shimojo, Masafumi, Zhou, Xiaoyun, Ono, Maiko, Matsuba, Yukio, Ji, Bin, Ishii, Hideki, Ogawa, Masanao, Akatsu, Hiroyasu, Kaneda, Daita, Hashizume, Yoshio, Robinson, John L, Lee, Virginia M -Y, Saito, Takashi, Saido, Takaomi C, Trojanowski, John Q, Zhang, Ming-Rong, Suhara, Tetsuya, Higuchi, Makoto, Sahara, Naruhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901060/ https://www.ncbi.nlm.nih.gov/pubmed/33644757 http://dx.doi.org/10.1093/braincomms/fcab011 |
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