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Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?

BACKGROUND: Ischemic stroke is an acquired brain injury with gender-dependent outcomes. A persistent obstacle in understanding the sex-specific neuroinflammatory contributions to ischemic brain injury is distinguishing between resident microglia and infiltrating macrophages—both phagocytes—and deter...

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Detalles Bibliográficos
Autores principales: Young, Kimberly F., Gardner, Rebeca, Sariana, Victoria, Whitman, Susan A., Bartlett, Mitchell J., Falk, Torsten, Morrison, Helena W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901206/
https://www.ncbi.nlm.nih.gov/pubmed/33618737
http://dx.doi.org/10.1186/s12974-021-02105-2