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Systemic administration of β-glucan induces immune training in microglia
BACKGROUND: An innate immune memory response can manifest in two ways: immune training and immune tolerance, which refers to an enhanced or suppressed immune response to a second challenge, respectively. Exposing monocytes to moderate-to-high amounts of bacterial lipopolysaccharide (LPS) induces imm...
Autores principales: | Heng, Yang, Zhang, Xiaoming, Borggrewe, Malte, van Weering, Hilmar R. J., Brummer, Maaike L., Nijboer, Tjalling W., Joosten, Leo A. B., Netea, Mihai G., Boddeke, Erik W. G. M., Laman, Jon D., Eggen, Bart J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901224/ https://www.ncbi.nlm.nih.gov/pubmed/33618716 http://dx.doi.org/10.1186/s12974-021-02103-4 |
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